Autoimmunity: Is antigen-specific suppression now unsuppressed?

Autoimmunity: Is antigen-specific suppression now unsuppressed?

Recent studies suggest that putative regulatory lymphocytes can effect antigen-specific down-regulation of autoimmunity. But we have yet to see how much this improves our picture of autoimmune disease progression.

Specific antigen(s) in sarcoidosis: a link to autoimmunity?

The nature of the activating antigen, however, has been an enigma over decades of sarcoidosis research. The histological similarities between sarcoidosis and tuberculosis, and the usefulness of tuberculin preparations in the Mendel-Mantoux test, led to the search for an antigen-containing extract, and in the middle of the last century, the first “antigen” was isolated from the spleen cells of p...

Age Specific Reference Levels of Serum Prostate-Specific Antigen, Prostate Volume and Prostate Specific Antigen Density in Healthy Iranian Men

Background: It is relevant to highlight that there is not a precise and perfect report on either 95 percentile value (upper limit of normal range) or on appropriate reference intervals for serum PSA in Iranian population. Objective: To determine age-specific reference ranges for serum prostate-specific antigen (PSA) concentration and PSA density (PSAD) and prostate volumes in a population of he...

Is There any Association between Thyroid Autoimmunity and Breast Cancer?

Background: The relationship between thyroid autoimmunity and breast cancer is a challenging subject. We aimed to investigate this association in women with breast cancer. Methods: In this descriptive study, 41 women with newly diagnosed breast cancer before receiving any pharmacologic treatment and 38 healthy age-matched women were enrolled. Anti TPO Ab (anti-thyroid peroxidase antibodies), FT...

Epistatic Suppression of Fatal Autoimmunity